MUSHA aims at creating future generations of bio-inspired tools and advanced bio-aware manipulation paradigms toward breakthrough mini-invasive surgical instruments and android robotic hands. Bio-inspired mechanical design leads to reduction of tools’ weight and dimension by limiting the number of actuators while preserving dexterity and manipulation capabilities. A fiber optic sensor is to be integrated to measure the contact forces exchanged with the environment and the temperature of the touched materials. MUSHA arises from the need to replicate human manipulation capabilities in various fields where robotics can help to improve life. These include unstructured environments in which a humanoid robot must replace the human being or parts of the body to address daily-life tasks, as well as minimally invasive robotic surgery where the surgeon is unable to use hands to manipulate organs and tissues while feeling their anatomy, consistency and temperature.